Alprazolam (Xanax) for sale in Australia

Description

Product Information

Alprazolam, commonly known by the brand name Xanax, is a potent triazolobenzodiazepine widely studied in pharmacological research. As a research chemical, it serves as a valuable tool for investigating GABA receptor modulation, anxiety mechanisms, and sedative-hypnotic effects. This article provides in-depth technical information optimized for researchers and educational purposes, emphasizing its role in controlled laboratory settings. http://reddit.com

Technical Details

Alprazolam is a white to off-white crystalline powder with a molecular weight of approximately 308.76 g/mol. It exhibits intermediate onset of action and is lipophilic, allowing good blood-brain barrier penetration in biological models. Key physicochemical properties include low water solubility but better solubility in organic solvents like ethanol or DMSO, making it suitable for various in vitro and in vivo research protocols.

It belongs to the benzodiazepine class, specifically triazolobenzodiazepines, distinguished by the fused triazole ring which contributes to its potency and pharmacokinetic profile.

Chemical Formula

Chemical Formula: C₁₇H₁₃ClN₄

CAS Number

CAS Number: 28981-97-7

Chemical Structure

The IUPAC name is 8-chloro-1-methyl-6-phenyl-4H-[1,2,4]triazolo[4,3-a][1,4]benzodiazepine. The structure features a benzodiazepine core with a triazole ring, a chlorine substituent at position 8, a methyl group at position 1, and a phenyl group at position 6. This configuration enhances its affinity for GABA_A receptors.

Common Research Applications

Alprazolam is extensively used in preclinical and clinical research models for:

• Anxiety and Panic Disorder Studies: Investigating mechanisms of generalized anxiety disorder (GAD) and panic attacks, including GABAergic neurotransmission and stress response modulation.
• Sedative-Hypnotic and Muscle Relaxant Research: Exploring CNS depression, sleep architecture, and anticonvulsant properties.
• Pharmacokinetic and Metabolism Studies: CYP3A4-mediated metabolism, half-life (typically 11-15 hours in models), and drug-drug interactions.
• Behavioral Neuroscience: Conditioned place preference (CPP), withdrawal syndromes, tolerance development, and dependence models in rodents.
• Comparative Benzodiazepine Efficacy: Head-to-head studies with other benzos for potency, onset, and duration.

Researchers also examine its potential in depression-associated anxiety and stress hormone (cortisol/ACTH) regulation.

Note: All applications are strictly for laboratory research and educational purposes. Not for human or veterinary therapeutic use.

Purity, Testing & Quality Assurance

High-purity Alprazolam (>98-99% by HPLC) is essential for reproducible research results. Quality assurance involves:

• High-Performance Liquid Chromatography (HPLC) for assay and impurity profiling.
• Nuclear Magnetic Resonance (NMR) and Mass Spectrometry (MS) for structural confirmation.
• Melting point verification and solubility testing.
• Heavy metals, residual solvents, and microbial limits testing per relevant pharmacopeial standards.

Reputable suppliers provide batch-specific Certificates of Analysis (COA) documenting these parameters to ensure research integrity.

Request the Current COA

Contact your trusted research chemical supplier directly to request the latest Certificate of Analysis (COA) for the specific batch of Alprazolam. The COA should include purity assay, impurity levels, identity confirmation, and expiration date. Always verify compliance with your institutional and local regulations before procurement.

Packaging Information

Research-grade Alprazolam is typically packaged in secure, tamper-evident glass vials or polyethylene bags under inert atmosphere to maintain stability. Common quantities include 10mg, 50mg, 100mg, or bulk for lab use. Outer packaging often features desiccant packets and clear labeling with CAS number, batch/lot number, and “For Research Use Only” warnings. Store in a cool, dry place away from light.

Precautions

Handle with standard laboratory safety protocols: use gloves, eye protection, and work in a fume hood. Alprazolam is a potent CNS depressant; avoid inhalation, ingestion, or skin contact. It may cause drowsiness, dizziness, or respiratory depression in exposure scenarios. Pregnant individuals or those with respiratory conditions should exercise extreme caution. Dispose of waste according to local hazardous materials regulations.

Disclaimer

This article is for informational and educational purposes only, focusing on the technical and research aspects of Alprazolam as a chemical compound. It does not constitute medical advice, diagnosis, or treatment recommendations. The product is strictly intended for research and forensic applications. Compliance with all applicable laws, institutional review board (IRB) approvals, and controlled substance regulations is the sole responsibility of the researcher. Potential for abuse and dependence exists; misuse is illegal and dangerous.

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